A 13-year-old Sicilian girl must contend with a viral contagion that has killed off all adults on the island as she sets out in search of her kidnapped brother.
When Astor dreams of his mother, she tells him to go back to his sister. Anna returns home, broken, but reunited with Astor. The siblings decide to set off for Italy, hopeful that someone has managed to find an antidote for the Red Fever.