Chris Rock
Osmosis Jones (voice)
Laurence Fishburne
Thrax (voice)
David Hyde Pierce
Drix (voice)
Brandy Norwood
Leah (voice)
Bill Murray
Frank Detorre
Molly Shannon
Mrs. Boyd
William Shatner
Mayor Phlegmming (voice)
Ron Howard
Tom Colonic (voice)
Sherry Lynn
(voice)
Mickie McGowan
Additional Character Voice (voice)
Chris Elliott
Bob
Elena Franklin
Shane Detorre
Kid Rock
Kidney Rock
Uncle Kracker
Kidney Rock (voice)
Carlos Alazraqui
Additional Character Voices (voice)
Rodger Bumpass
Additional Character Voices (voice)
Richard Steven Horvitz
Additional Character Voices (voice)
Danny Mann
Additional Character Voices (voice)
Mickie McGowan
Additional Character Voices (voice)
Jonathan Adams
Additional Character Voices (voice)
Bobby Farrelly
Director
Marc Hyman
Screenplay
Bobby Farrelly
Producer
Peter Farrelly
Producer
Zak Penn
Producer
Bradley Thomas
Producer
Randy Edelman
Original Music Composer
Mark Irwin
Director of Photography
Lois Freeman-Fox
Editor
Stephen Schaffer
Editor
Sam Seig
Editor
Peter Farrelly
Director
Adam Beck
Animation
Paul Dutton
Animation
Jeannine Berger
Post Production Supervisor
Audrey Stedman
Layout
Karen Hamrock
Layout
Bob Camp
Storyboard
Eddie Rosas
Animation
Bill Perkins
Layout
Jennifer Yuan
Layout
Earl A. Hibbert
Visual Effects
Marc S. Fischer
Co-Producer
Aaron Parry
Associate Producer
John Walker
Associate Producer
Arlan Jay Vetter
Art Direction
Chris Aguirre
Visual Development
Mark Andrews
Storyboard
Barry Caldwell
Storyboard
Ruben Chavez
Visual Development
Katherine C. Concepcion
Art Department Manager
Ricardo F. Delgado
Visual Development
Hani D. El-Masri
Visual Development
Jeff Etter
Visual Development
Steve Fonti
Storyboard
Darek Gogol
Visual Development
Daan Jippes
Storyboard
Kevin Johnson
Visual Development
Leon Delaney
Stunt Coordinator
John Bermudes
Special Effects
John Harajovic
Special Effects
William 'Billy Jack' Jakielaszek
Special Effects Coordinator
Carol Koch
Sculptor
Craig R. Maras
Animation
Randy Sanchez
Animation
James P. Alles
Layout
John Williamson
Animation
Joe Giampapa
Animation
Sam Chou
Animation
Shane Prigmore
Animation
Fred Cline
Visual Development
Stephan Franck
Lead Animator
Ian Mah
Visual Effects Supervisor
Darlie Brewster
Supervising Animator
Rick Montgomery
Casting
Steven Burch
Special Effects Supervisor
Sydney J. Bartholomew Jr.
Production Design
Scott Jacobson
Set Decoration
Pamela Withers
Costume Design
Brenda McNally
Hair Department Head
Joe Rossi
Makeup Department Head
Hal Olofsson
First Assistant Director
Ken Ross
Music Supervisor
Randy Thom
Sound Designer
Dennis Edwards
Producer
Alan J. Hagge
Systems Administrators & Support
Louis Gonzales
Layout
Moroni Taylor
Storyboard Artist