Desde Gayola is a Mexican late-night live television sketch comedy and variety show created by Horacio Villalobos. The show premiered on the music videos network Telehit on November 21, 2001, as a sketch into the variety show Válvula de Escape. The show revolves around a series of parodying Mexican culture, sexuality and politics performed by a large and varying cast of repertory and newer cast members.
The TV show followed a format similar to the famous American show Saturday Night Live with each episode approximately 25 minutes in length and containing an average of five sketches per episode. The show included several transgender actors, who interpret female characters.