John Cusack
Igor (voice)
Myleene Klass
Dr. Holzwurm (voice)
Robin Walsh
Dr. Holzwurm's Igor (voice)
Matt McKenna
Dr. Herzschlag (voice)
John Cleese
Dr. Glickenstein (voice)
Steve Buscemi
Scamper (voice)
Sean Hayes
Brain (voice)
Eddie Izzard
Dr. Schadenfreude (voice)
Jay Leno
King Malbert (voice)
Jennifer Coolidge
Jaclyn / Heidi (voice)
Molly Shannon
Eva (voice)
James Lipton
Himself
Christian Slater
Dr. Schadenfreude's Igor (voice)
Arsenio Hall
Carl Cristall (voice)
Jess Harnell
Announcer / Royal Guard #2 (voice)
Zoë Bright
Blind Woman / Killiseum Fan #1 (voice)
Sophia Eraklis
Blind Orphan #1 (voice)
A. Cheron Hall
Blind Orphan #2 / Blind Orphan #4 (voice)
Alexander Leondis
Blind Orphan #3 (voice)
Michael Leondis
Blind Orphan #6 (voice)
Nicole Leondis
Blind Orphan #7 (voice)
Juliana Leondis
Blind Orphan #5 (voice)
Robin Tisserand
Blind Orphan #8 (voice)
Paul Vogt
Buzz Offmann (voice)
Frank Welker
Animals' vocal effects (voice) (uncredited)
Tony Leondis
Director
John Hoffman
Screenplay
Dimitri Toscas
Screenplay
Tony Leondis
Screenplay
Chris McKenna
Screenplay
Steven Clay Hunter
Animation
Jean-Luc De Fanti
Executive Producer
Jamée Deruso
Associate Producer
John D. Eraklis
Producer
Max Howard
Producer
Darius A. Kamali
Associate Producer
Matthew J. Parker
Associate Producer
Patrick Doyle
Original Music Composer
Hervé Schneid
Editor
Loïc Rastout
Production Design
Olivier Besson
Art Direction
Zoltán Maros
Animation